Search Result

Search Results for " epidermal growth factor "

Targets

210

Compounds

Natural Products

Recombinant Proteins

Libraries

Cat No.	Product Name	Synonyms	Targets
T8679	Epidermal Growth Factor		EGFR
	Epidermal Growth Factor binds to epidermal growth factor receptor (EGFR) and stimulates cell growth and proliferation. It is approved for the treatment of diabetic foot ulcers.		EGFR
T21723L	Epidermal Growth Factor Receptor Peptide Acetate	Epidermal Growth Factor Receptor Peptide Acetate(96249-43-3 Free base)	Others
	Epidermal Growth Factor Receptor Peptide Acetate (Epidermal Growth Factor Receptor Peptide Acetate(96249-43-3 Free base)) exists on the cell surface and is activated by the binding of its specific ligands.EGFR belongs t...		Others
TP2229	Epidermal growth factor receptor (994-1002) acetyl/amide		Others
	The epidermal growth factor receptor is the cell-surface receptor for members of the epidermal growth factor family of extracellular protein ligands.		Others
T3466	FIIN-3		EGFR , FGFR
	FIIN-3 is an irreversible inhibitor of FGFR.		EGFR , FGFR
T5475	ZD-4190		EGFR , VEGFR
	ZD-4190 is a compound that inhibits both the vascular endothelial growth factor receptor 2 (VEGFR2) and the epidermal growth factor receptor (EGFR) signaling pathways, utilized in cancer treatment.		EGFR , VEGFR
T2705	Mutant EGFR inhibitor		EGFR
	Mutant EGFR inhibitor is a selective and potent Mutated EGFR inhibitor, inhibits L858R activating mutant, the Exonl9 deletion activating mutant and the T790M resistance mutant.		EGFR
T11160	EGFR-IN-5		EGFR
	EGFR-IN-5 is a selective inhibitor of EGFR. The IC50s for EGFR, EGFR(L858R), EGFR(L858R/T790M), and EGFR(L858R/T790M/C797S) are 10.4, 1.1, 34, 7.2 nM, respectively.		EGFR
T8976	PD-089828		EGFR , FGFR , PDGFR , Src
	PD 089828 is a competitive inhibitor of the receptor tyrosine kinases FGFR1, PDGFRβ, and EGFR (IC50s = 0.15, 1.76, and 5.47 µM, respectively) and a noncompetitive inhibitor of the nonreceptor tyrosine kinase c-Src (IC50 ...		EGFR , FGFR , PDGFR , Src
T16343	NRC-2694		EGFR
	NRC-2694 is an antagonist of the epidermal growth factor receptor (EGFR). It has anti-cancer and anti-proliferative properties.		EGFR
T23176	PP 3		Src
	PP 3 is a Negative control for the Src kinase inhibitor PP 2		Src
T2491	AZ-5104		EGFR
	AZ5104 is a potent EGFR inhibitor.		EGFR
T11162	EGFR-IN-8		EGFR , c-Met/HGFR
	EGFR-IN-8, a dual inhibitor targeting both EGFR and c-Met, shows potential as a promising candidate for further development in treating EGFR TKI-resistant NSCLC.		EGFR , c-Met/HGFR
T7819	TAS0728		EGFR , HER
	TAS0728 is a HER2 inhibitor, with antitumor activity		EGFR , HER
T10534	BI-4020		EGFR
	BI-4020 is a fourth-generation, orally active, and non-covalent inhibitor of EGFR tyrosine kinase. BI-4020 exhibits activity agains the triple mutant EGFR del19 T790M C797S variant (IC50=0.2 nM in BaF3 cell lines), the d...		EGFR
T5410	PD158780		EGFR
	PD 158780 reversibly inhibits auto and transphosphorylation of all four members of the ErbB receptor superfamily: EGFR, ErbB2, ErbB3, and ErbB4 (IC50s: 8μM, 49 nM, 52 nM, and 52 nM in cell assay).		EGFR
T6733	WZ-3146		EGFR
	WZ3146 is a mutant-selective irreversible inhibitor of EGFR(L858R) and EGFR(E746_A750) with IC50 of 2 nM and 2 nM; does not inhibit ERBB2 phosphorylation (T798I).		EGFR
T23127	PD-161570	PD 161570	EGFR , FGFR , PDGFR , Src
	PD-161570 is a potent and ATP-competitive human FGF-1 receptor inhibitor with an IC50 of 39.9 nM and a Ki of 42 nM. PD-161570 also inhibits the PDGFR, EGFR and c-Src tyrosine kinases with IC50 values of 310 nM, 240 nM, a...		EGFR , FGFR , PDGFR , Src
T4296	MTX-211	MTX 211	EGFR , PI3K
	MTX-211, an inhibitor of EGFR and PI3K, is used for the therapy of cancer and other diseases.		EGFR , PI3K
T6824	EAI045		EGFR
	EAI045, an allosteric inhibitor, targets towards drug-resistant EGFR mutants but avoids the wild-type receptor.		EGFR
T6238	WZ4002		EGFR
	WZ4002 is a mutant-selective EGFR inhibitor for EGFR(L858R) and EGFR(T790M) with IC50 of 2 nM/8 nM.		EGFR
T17182	TX1-85-1		EGFR
	TX1-85-1 induces partial degradation of Her3 protein and attenuates Her3-dependent signaling. TX1-85-1 is an irreversible Her3 inhibitor (IC50: 23 nM). TX1-85-1 is also the first selective Her3 ligand, which forms a cova...		EGFR
T11569	HKI-357		EGFR
	HKI-357 is an irreversible dual inhibitor of EGFR and ERBB2 (IC50s: 34 nM and 33 nM). HKI-357 suppresses EGFR autophosphorylation (at Y1068), and AKT and MAPK phosphorylation.		EGFR
T9912	Trastuzumab		EGFR
	Trastuzumab is a humanized monoclonal antibody for patients with invasive breast cancers that overexpress HER2. Trastuzumab has been clinically used to treat HER2 Positive Metastatic Breast Cancer and HER2 Positive Gastr...		EGFR
T3659	Zorifertinib	AZD3759	EGFR
	Zorifertinib (AZD3759) is an orally active, effective and central nervous system-penetrant EGFR inhibitor. The IC50 values were 0.2, 0.3 and 0.2 nM for EGFR L858R mutant, TK wild-type, and Exon 19Del enzymes, respectivel...		EGFR
T6008	CNX-2006	CNX 2006,CNX2006	EGFR
	CNX-2006 is a novel irreversible mutant-selective EGFR inhibitor with IC50 of < 20 nM, with very weak inhibition at wild-type EGFR.		EGFR
T2034	AG1557	AG-1557,AG 1557	EGFR , HER
	AG1557 (AG-1557) is an inhibitor of the epidermal growth factor receptor (EGFR) tyrosine kinase (pIC50: 8.194).		EGFR , HER
T6734	WZ8040		EGFR
	WZ8040 is a novel mutant-selective irreversible EGFRT790M inhibitor, does not inhibit ERBB2 phosphorylation (T798I).		EGFR
TQ0092	Naquotinib	ASP8273	EGFR
	Naquotinib (ASP8273) (ASP8273) is an orally available, mutant-selective and irreversible EGFR inhibitor; (IC50s: 8-33 nM and 230 nM toward EGFR mutants and EGFR.		EGFR
T13564	AZ7550		MLK , FAK , EGFR , FLT , Tyrosine Kinases , PYK2 , MNK , IGF-1R , ACK , BTK , ALK , Drug Metabolite
	AZ7550, an active metabolite of AZD9291, inhibits the activity of IGF1R (IC50: 1.6 μM).
T11161	EGFR-IN-7	TQB3804	EGFR
	EGFR-IN-7 (TQB3804) is a selective and potent EGFR kinase inhibitor.		EGFR
T8431	JCN037		EGFR
	JCN037 is potent, non-covalent and brain-penetrant inhibitor of EGFR(EGFR, p-wtEGFR and pEGFRvⅢ with IC50 of 2.49 nM, 3.95 nM, 4.48 nM , respectively).		EGFR
T16369	O-Desmethyl gefitinib		EGFR
	O-Desmethyl gefitinib inhibits EGFR (IC50: 36 nM in subcellular assays). In human plasma, O-Desmethyl gefitinib is an active metabolite of Gefitinib. The formation of O-desmethyl gefitinib is dependent on the CYP2D6 acti...		EGFR
T2032	WHI-P180	Janex 3	EGFR , VEGFR , c-RET , CDK
	WHI-P180 (Janex 3) is a potent EGFR and Cdk2 inhibitors with IC50 of 4.0 and 1.0 uM, respectively.		EGFR , VEGFR , c-RET , CDK
T5437	Gefitinib-based PROTAC 3		EGFR
	Gefitinib-based PROTAC 3, conjugating an EGFR binding element to a VHL ligand via a linker, induces EGFR degradation with DC50s of 11.7 nM and 22.3 nM in HCC827(exon 19 del) and H3255 (L858R mutantion) cells, respectivel...		EGFR
T8534	Tyrphostin AG 112		EGFR
	Tyrphostin AG 112 is an inhibitor of EGFR phosphorylation.		EGFR
T3108	CUDC-101	CUDC 101,CUDC101	EGFR , HER , HDAC
	CUDC-101 is a potent inhibitor of HDAC, EGFR and HER2 with IC50s of 4.4, 2.4 and 15.7 nM, respectively.		EGFR , HER , HDAC
T13088	Tarloxotinib bromide	TH-4000	EGFR , HER
	Tarloxotinib bromide (TH-4000) is an irreversible inhibitor of EGFR/HER2.		EGFR , HER
T6932	PD168393		Apoptosis , EGFR , FGFR , IGF-1R , PDGFR , PKC , Autophagy
	PD168393 is an irreversible EGFR inhibitor (IC50: 0.70 nM), irreversibly alkylate Cys-773; inactive against PKC, FGFR, PDGFR, and insulin.		Apoptosis , EGFR , FGFR , IGF-1R , PDGFR , PKC , Autophagy
T6124	Mubritinib	TAK-165	EGFR , FGFR , JAK , PDGFR
	Mubritinib (TAK-165) (TAK-165) is a potent inhibitor of HER2/ErbB2 with IC50 of 6 nM.		EGFR , FGFR , JAK , PDGFR
T6039	TAK-285	TAK285,TAK 285	EGFR , MEK , HER , Aurora Kinase
	TAK-285 is a novel dual HER2 and EGFR(HER1) inhibitor with IC50 of 17 nM and 23 nM, >10-fold selectivity for HER1/2 than HER4, less potent to MEK1/5, c-Met, Aurora B, Lck, CSK etc. Phase 1.		EGFR , MEK , HER , Aurora Kinase
T6092	Sapitinib	AZD-8931	EGFR
	Sapitinib (AZD-8931) , a reversible, ATP competitive inhibitor of EGFR(IC50=4 nM), ErbB2(IC50=3 nM) and ErbB3(IC50=4 nM), is more effective over Gefitinib or Lapatinib against NSCLC cell, 100-fold more specific for the E...		EGFR
T6908	NSC 228155	NSC228155	EGFR , Epigenetic Reader Domain , DNA/RNA Synthesis , Histone Acetyltransferase
	NSC 228155 is an activator of EGFR, binding to the sEGFR dimerization domain II and modulate EGFR tyrosine phosphorylation.
T22396	PF-6274484	PF 6274484	EGFR
	PF-6274484, a high affinity, irreversible covalent inhibitor of EGFR kinase with Ki of 0.14 nM, inhibits the autophosphorylation of wild-type EGFR in A549 cells and EGFRL858R/T790M in H1975 cells with IC50 of 5.8 nM and ...		EGFR
T21853	(E)-AG 556		EGFR
	AG 556 is a selective inhibitor of EGFR and blocks LPS-induced TNF-α production.		EGFR
T22431	SU5204	3-[(2-Ethoxyphenyl)methylidene]-1H-indol-2-one	EGFR , VEGFR , HER
	SU5204 (3-[(2-Ethoxyphenyl)methylidene]-1H-indol-2-one), an analogue of SU5025, pharmacologically inhibits VEGFR2(IC50s of 4 and 51.5 μM for FLK-1 (VEGFR-2) and HER2)		EGFR , VEGFR , HER
T9927	Panitumumab		EGFR
	Panitumumab is a fully human IgG2 monoclonal antibody targeting the epidermal growth factor receptor EGFR).		EGFR
T4014	CP-724714	CP724714,CP 724714	Apoptosis , EGFR
	CP-724714 (CP724714) is an effective and selective HER2/ErbB2 inhibitor (IC50: 10 nM), >640-fold selectivity against EGFR, Abl, InsR, PDGFR, IRG-1R, Src, VEGFR2, c-Met etc.		Apoptosis , EGFR
T10419	AV-412	MP412	EGFR
	AV-412 (MP412) is an EGFR inhibitor (EGFR, EGFR T790M, EGFR L858R, EGFR L858R/T790M and ErbB2 with IC50s of 0.75, 0.79, 0.5, 2.3, 19 nM).		EGFR
T8151	Mobocertinib	tak788	EGFR
	Mobocertinib (tak788) is a potent inhibitor of epidermal growth factor receptor (EGFR) and an antineoplastic agent		EGFR
T3024	Avitinib	AC0010	EGFR , JAK , BTK
	Avitinib (AC0010), also known as AC0010 or AC0010MA, is an orally available, irreversible, epidermal growth factor receptor (EGFR) mutant-selective inhibitor, with potential antineoplastic activity. Upon oral administrat...		EGFR , JAK , BTK

Compounds

Epidermal Growth Factor

T8679

Synonym:

Target: EGFR

Epidermal Growth Factor Receptor Peptide Acetate

T21723L

Synonym: Epidermal Growth Factor Receptor Peptide Acetate(96249-43-3 Free base)

Target: Others

Epidermal growth factor receptor (994-1002) acetyl/amide

Mutant EGFR inhibitor

Target: EGFR, FGFR, PDGFR, Src

Target: EGFR, c-Met/HGFR

Target: EGFR, FGFR, PDGFR, Src

Synonym: CNX 2006,CNX2006

Target: EGFR

AG1557

T2034

Synonym: AG-1557,AG 1557

Target: MLK, FAK, EGFR, FLT, Tyrosine Kinases, PYK2, MNK, IGF-1R, ACK, BTK, ALK, Drug Metabolite

O-Desmethyl gefitinib

Target: EGFR, VEGFR, c-RET, CDK

Gefitinib-based PROTAC 3

Synonym: CUDC 101,CUDC101

Target: EGFR, HER, HDAC

Target: Apoptosis, EGFR, FGFR, IGF-1R, PDGFR, PKC, Autophagy

Mubritinib

T6124

Synonym: TAK-165

Target: EGFR, FGFR, JAK, PDGFR

TAK-285

T6039

Synonym: TAK285,TAK 285

Target: EGFR, MEK, HER, Aurora Kinase

Target: EGFR, Epigenetic Reader Domain, DNA/RNA Synthesis, Histone Acetyltransferase

Synonym: 3-[(2-Ethoxyphenyl)methylidene]-1H-indol-2-one

Target: EGFR, VEGFR, HER

Synonym: CP724714,CP 724714

Target: Apoptosis, EGFR

Target: EGFR, JAK, BTK

Cat No.	Product Name	Synonyms	Targets
TL0016	Sulforaphene		Apoptosis , ERK , EGFR , NF-κB
	Sulforaphene is a natural product isolated from radish seeds, exhibits an ED50 against velvetleaf seedlings approximately 2 x 10 -4 M. Sulforaphene promotes cancer cells apoptosis and inhibits migration via inhibiting EG...		Apoptosis , ERK , EGFR , NF-κB
T22974	Methyl 2,5-dihydroxycinnamate		EGFR
	EGF receptor-associated tyrosine kinases inhibitor		EGFR
TN1440	Beta-Hydroxyisovalerylshikonin		EGFR , Tyrosine Kinases , Prostaglandin Receptor , Src , AMPK , Fatty Acid Synthase
	Beta-Hydroxyisovalerylshikonin is an inhibitor of protein-tyrosine kinases such as v-Src and EGFR, and has been shown to induce apoptosis in several human tumor cell lines. Beta-Hydroxyisovalerylshikonin significantly de...
T3870	Cyasterone	Cyasteron	Apoptosis , EGFR
	Cyasterone (Cyasteron), a natural EGFR inhibitor, can inhibit the growth of A549 and MGC823 cells, via regulating EGFR signaling pathway, it may be a promising anti-cancer agent. Cyasterone has antifeeding activity.		Apoptosis , EGFR
T1431	Khellin	Amicardine,Methafrone,Visammin	EGFR , Others
	Khellin (Methafrone) is a vasodilator that also has bronchodilatory action.		EGFR , Others
T2995	Chrysophanol	3-Methylchrysazin,Chrysophanic Acid,Turkey Rhubarb	EGFR
	Chrysophanol (Turkey Rhubarb) is an EGFR/mTOR pathway inhibitor, which can be found in rhubarb, and sorrel.		EGFR
T1737	Genistein	NPI 031L	Apoptosis , EGFR , Endogenous Metabolite , Autophagy
	Genistein (NPI 031L) is an isoflavonoid derived from soy products. It inhibits protein-tyrosine kinase and topoisomerase-II (DNA TOPOISOMERASES, TYPE II), with antineoplastic and antitumor activities.		Apoptosis , EGFR , Endogenous Metabolite , Autophagy
T4183	Lavendustin A	RG-14355,NSC 678027	EGFR , Tyrosinase
	lavendustin A (RG-14355) is a potent, cell-permeable inhibitor of epidermal growth factor receptor (EGFR) tyrosine kinase.		EGFR , Tyrosinase
T6427	Butein	2’,3,4,4’-tetrahydroxy Chalcone	Apoptosis , EGFR , Others , PDE , Autophagy
	Butein (2’,3,4,4’-tetrahydroxy Chalcone), a plant polyphenol, is isolated from Rhus verniciflua. It can inhibit the activation of protein tyrosine kinase, NF-κB and STAT3, and also can inhibit EGFR.		Apoptosis , EGFR , Others , PDE , Autophagy
T1181	Gefitinib	ZD1839	EGFR , Tyrosine Kinases , Autophagy
	Gefitinib (ZD1839) is an EGFR first-generation inhibitor with oral activity that inhibits the EGFR 19 Del and L858R mutations. Gefitinib has antitumor activity and is used for the treatment of EGFR-mutated non-small-cell...		EGFR , Tyrosine Kinases , Autophagy
T2851	Daphnetin	7,8-Dihydroxycoumarin,Daphnetol	EGFR , PKA , PKC , Parasite , Autophagy
	Daphnetin (7,8-Dihydroxycoumarin), a natural coumarin derivative, is a protein kinase inhibitor with inhibitory for EGFR (IC50: 7.67 μM), PKA (IC50: 9.33 μM), and PKC (IC50: 25.01 μM), also exhibit anti-oxidant and anti-...		EGFR , PKA , PKC , Parasite , Autophagy
T6943	Picropodophyllin	AXL1717,Picropodophyllin (PPP),Picropodophyllotoxin,PPP	Apoptosis , IGF-1R
	Picropodophyllin (Picropodophyllin (PPP)) (PPP) is a specific IGF-1R inhibitor (IC50: 1 nM). Picropodophyllin specifically inhibits the activity and downregulates the cellular expression of IGF1R without interfering with...		Apoptosis , IGF-1R
T3S0027	Picropodophyllotoxin	AXL 1717,Picropodophyllin	IGF-1R
	Picropodophyllotoxin (AXL 1717) is a cyclolignan alkaloid found in the mayapple plant family (Podophyllum peltatum), and a small molecule inhibitor of the insulin-like growth factor 1 receptor (IGF1R) with potential anti...		IGF-1R
TN3711	Corylifol C		ERK , EGFR , p38 MAPK , MEK
	Corylifol C and, to a lesser extent, xanthoangelol are potent protein kinase inhibitors (inhibitory concentration 50% values for epidermal growth factor receptor (EGFR): 1.1 and 4.4 × 10(-6) μg/ml, respectively).		ERK , EGFR , p38 MAPK , MEK
TN2504	1,5-Dihydroxyxanthone		EGFR , AChR
	1,5-Dihydroxyxanthone exhibits the epidermal growth factor receptor (EGFR) -tyrosine kinase inhibitory activity, with the IC50 value of 90.34 nM. It may have anticholinesterase activity on acetylcholinesterase (AChE) and...		EGFR , AChR
T75487	7-Hydroxyneolamellarin A
	7-Hydroxyneolamellarin A, a natural product from the sponge Dendrilla nigra, serves as a potent inhibitor of hypoxia-inducible factor-1α (HIF-1α). It effectively reduces the accumulation of HIF-1α protein and suppresses ...
T37008	Reveromycin A
	Reveromycin A is the major component of a complex of spiroketal antibiotics isolated from Streptomyces sp. It inhibits the mitogenic activity of epidermal growth factor in Balb/MK cells (IC50 = 0.7 μg/ml), displays antip...

Natural Products

Sulforaphene

TL0016

Synonym:

Target: Apoptosis, ERK, EGFR, NF-κB

Methyl 2,5-dihydroxycinnamate

T22974

Synonym:

Target: EGFR

Beta-Hydroxyisovalerylshikonin

TN1440

Synonym:

Target: EGFR, Tyrosine Kinases, Prostaglandin Receptor, Src, AMPK, Fatty Acid Synthase

Cyasterone

T3870

Synonym: Cyasteron

Target: Apoptosis, EGFR

Khellin

T1431

Synonym: Amicardine,Methafrone,Visammin

Target: EGFR, Others

Chrysophanol

T2995

Synonym: 3-Methylchrysazin,Chrysophanic Acid,Turkey Rhubarb

Target: Apoptosis, EGFR, Endogenous Metabolite, Autophagy

lavendustin A

T4183

Synonym: RG-14355,NSC 678027

Target: EGFR, Tyrosinase

Butein

T6427

Synonym: 2’,3,4,4’-tetrahydroxy Chalcone

Target: Apoptosis, EGFR, Others, PDE, Autophagy

Gefitinib

T1181

Synonym: ZD1839

Target: EGFR, Tyrosine Kinases, Autophagy

Daphnetin

T2851

Synonym: 7,8-Dihydroxycoumarin,Daphnetol

Target: EGFR, PKA, PKC, Parasite, Autophagy

Picropodophyllin

T6943

Synonym: AXL1717,Picropodophyllin (PPP),Picropodophyllotoxin,PPP

Target: Apoptosis, IGF-1R

Picropodophyllotoxin

T3S0027

Synonym: AXL 1717,Picropodophyllin

Target: ERK, EGFR, p38 MAPK, MEK

1,5-Dihydroxyxanthone

TN2504

Synonym:

Target: EGFR, AChR

7-Hydroxyneolamellarin A

Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPY-04818	EGFR Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293 Cells
	EGFR Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 70.1 kDa and the accession number is A0A2K5WK39.
TMPY-06984	EGF Protein, Mouse, Recombinant (Yeast)	Mouse	P. pastoris (Yeast)
	EGF Protein, Mouse, Recombinant (Yeast) is expressed in yeast. The predicted molecular weight is 6 KDa. and the accession number is P01132.
TMPY-01560	EGF Protein, Human, Recombinant	Human	E. coli
	EGF Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 6.35 kDa and the accession number is P01133-1.
TMPY-01062	EGF Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	EGF Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 33 kDa and the accession number is P01133-1.
TMPY-02676	EGFR Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	EGFR Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 70.8 kDa and the accession number is Q01279.
TMPY-04529	EGFR Protein, Human, Recombinant (aa 668-1210, His & GST)	Human	Baculovirus Insect Cells
	EGFR Protein, Human, Recombinant (aa 668-1210, His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 89.1 kDa and the accession number is P00533-1.
TMPY-00742	EGFR Protein, Human, Recombinant (His)	Human	HEK293 Cells
	EGFR Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 69.8 kDa and the accession number is P00533-1.
TMPY-04220	EGF Protein, Rat, Recombinant	Rat	E. coli
	EGF Protein, Rat, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 6.3 kDa and the accession number is P07522.
TMPY-02958	EGFR Protein, Rat, Recombinant (His)	Rat	HEK293 Cells
	EGFR Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 70.7 kDa and the accession number is E7CXR8.
TMPY-03724	EGFR Protein, Canine, Recombinant (His)	Canine	Baculovirus Insect Cells
	EGFR Protein, Canine, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 69.8 kDa and the accession number is XP_533073.3.
TMPY-06524	EGFR Protein, Feline, Recombinant (His)	Feline	Baculovirus Insect Cells
	EGFR Protein, Feline, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 70.18 kDa and the accession number is A0A337S424.
TMPY-00128	EGFR Protein, Rhesus, Recombinant (hFc)	Rhesus	HEK293 Cells
	EGFR Protein, Rhesus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 95.4 kDa and the accession number is XP_001107305.1.
TMPY-04884	EGF Protein, Canine, Recombinant	Canine	P. pastoris (Yeast)
	EGF Protein, Canine, Recombinant is expressed in yeast. The predicted molecular weight is 6.2 kDa and the accession number is Q9BEA0.
TMPY-02539	EGF Protein, Canine, Recombinant (His)	Canine	E. coli
	EGF Protein, Canine, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 8.3 kDa and the accession number is Q9BEA0.
TMPY-06493	EGF Protein, Feline, Recombinant (hFc)	Feline	HEK293 Cells
	EGF Protein, Feline, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 34.63 kDa and the accession number is NP_001009381.1.
TMPY-02267	EGF Protein, Mouse, Recombinant (hFc)	Mouse	HEK293 Cells
	EGF Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 34.5 kDa and the accession number is P01132.
TMPY-00220	EGF Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	EGF Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 111.3 kDa and the accession number is AAH60741.1.
TMPY-02675	EGFR Protein, Mouse, Recombinant (hFc)	Mouse	HEK293 Cells
	EGFR Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 96 kDa and the accession number is Q01279.
TMPJ-00058	BTC Protein, Mouse, Recombinant (His)	Mouse	E. coli
	Mouse Betacellulin is a single type I membrane protein which belongs to the EGF family of cytokines. EGF family has many members including EGF, TGF-a, Amphiregulin, HB-EGF, Epiregulin, Tomoregulin and the Neuregulins. Be...
TMPJ-01286	ProHB-EGF Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Heparin-binding EGF-like growth factor (HB-EGF) is a 1216 kDa member of the epidermal growth factor (EGF) family. It possesses an EGFlike domain, and a heparin-binding motif. Mature HBEGF is a soluble peptide that ari...
TMPY-05211	EGFR Protein, Human, Recombinant (Isoform vIII, aa 1-375, His)	Human	Baculovirus Insect Cells
	EGFR Protein, Human, Recombinant (Isoform vIII, aa 1-375, His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 39.3 kDa and the accession number is NP_001333870.1.
TMPY-05612	EGFR Protein, Human, Recombinant (aa 1-645, His & Avi), Biotinylated	Human	HEK293 Cells
	EGFR Protein, Human, Recombinant (aa 1-645, His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 71.9 kDa and the accession number is P00533-1.
TMPY-05637	EGFR Protein, Human, Recombinant (aa 1-378, His & Avi), Biotinylated	Human	Baculovirus Insect Cells
	EGFR Protein, Human, Recombinant (aa 1-378, His & Avi), Biotinylated is expressed in Baculovirus insect cells with His and Avi tag. The predicted molecular weight is 41.8 kDa and the accession number is NP_001333870.1.
TMPY-05258	EGFR Protein, Human, Recombinant (Isoform Viii, hFc)	Human	Baculovirus Insect Cells
	EGFR Protein, Human, Recombinant (Isoform Viii, hFc) is expressed in Baculovirus insect cells with hFc tag. The predicted molecular weight is 65.1 kDa and the accession number is NP_001333870.1.
TMPY-06593	EGFR Protein, Human, Recombinant (Isoform vIII, His & Avi), Biotinylated	Human	HEK293 Cells
	EGFR Protein, Human, Recombinant (Isoform vIII, His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 41.90 kDa and the accession number is NP_001333870.1...
TMPY-01043	EGFR Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	EGFR Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 95 kDa and the accession number is P00533-1.
TMPY-06549	EGFR Protein, Human, Recombinant (Isoform vIII, aa 1-378, His)	Human	HEK293 Cells
	EGFR Protein, Human, Recombinant (Isoform vIII, aa 1-378, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 40.09 kDa and the accession number is NP_001333870.1.
TMPJ-00646	EGFR vIII Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293 Cells
	EGFR vIII Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-6xHis-Avi tag. The predicted molecular weight is 60-90 KDa and the accession number is NP_001333870.
TMPJ-00648	EGFR vIII Protein, Human, Recombinant (His)	Human	HEK293 Cells
	EGFR vIII Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 61-75 Kda and the accession number is NP_001333870.
TMPJ-00647	EGFR vIII Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	EGFR vIII Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 90-120 KDa and the accession number is NP_001333870.
TMPH-02645	EGFL8 Protein, Mouse, Recombinant (His & Myc & SUMO)	Mouse	E. coli
	N/A. EGFL8 Protein, Mouse, Recombinant (His & Myc & SUMO) is expressed in E. coli expression system with N-10xHis-SUMO and C-Myc tag. The predicted molecular weight is 49.0 kDa and the accession number is Q6GUQ1.
TMPK-01073	CLEC14A Protein, Human, Recombinant (His)	Human	HEK293 Cells
	CLEC14A is a single-pass transmembrane glycoprotein belonging to the vascular expressed C-type lectin family. CLEC14A is found to be expressed in vascular endothelial cells during embryogenesis and is also implicated in ...
TMPJ-00791	HER2/ERBB2 Protein, Rat, Recombinant (E. coli, His)	Rat	E. coli
	ERBB2 belongs to the protein kinase superfamily, Tyr protein kinase family and EGF receptor subfamily. It contains a protein kinase domain. ERBB2 is widely expressed in epithelial cells, and amplification and/or overexpr...
TMPY-04125	PTP1B Protein, Human, Recombinant (His)	Human	E. coli
	PTP1B, also known as PTPN1, belongs to the protein-tyrosine phosphatase (PTP) family. PTPs catalyze the hydrolysis of the phosphate monoesters specifically on tyrosine residues. Members of the PTP family share a highly c...
TMPY-01061	FGF-10 Protein, Human, Recombinant	Human	E. coli
	Fibroblast growth factor 10 (FGF10) is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes...
TMPY-01085	VLDLR Protein, Human, Recombinant (His)	Human	HEK293 Cells
	The very low density lipoprotein receptor, known as VLDLR, is a single-pass type 1 integral membrance protein and a member of the LDL receptor family. This receptor family includes LDL receptor, LRP, megalin, VLDLR and A...
TMPK-00428	HER2/ErbB2 Protein, Human, Recombinant (His & Avi)	Human	HEK293 Cells
	ErbB2, also called Neu and Her2 (human epidermal growth factor receptor 2), is a type I membrane glycoprotein that is a member of the ErbB family of tyrosine kinase receptors. ErbB family members serve as receptors for t...
TMPY-04202	Tomoregulin-1 Protein, Mouse, Recombinant (hFc)	Mouse	HEK293 Cells
	TMEFF1 is a novel transmembrane protein, containing two follisatin domains and an epidermal growth factor-like region. The ectopic expression of TMEFF1 in brain cancer cells resulted in their growth inhibition. That TMEF...
TMPY-00112	Tomoregulin-1 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	TMEFF1 is a novel transmembrane protein, containing two follisatin domains and an epidermal growth factor-like region. The ectopic expression of TMEFF1 in brain cancer cells resulted in their growth inhibition. That TMEF...
TMPY-02264	LRIG1 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	Leucine-rich repeats and immunoglobulin-like domains 1 (LRIG1) is a tumor suppressor and a negative regulator of several receptor tyrosine kinases. Leucine-rich repeats and immunoglobulin-like domains containing protein ...
TMPJ-00859	AREG Protein, Human, Recombinant	Human	E. coli
	Amphiregulin (AREG) is a single-pass membrane protein with 252 amino acids. AREG belongs to the amphiregulin family, which contains 1 EGF-like domain. AREG is expressed in a variety of tissues including ovary, placenta, ...
TMPK-00820	AREG Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	Amphiregulin (AREG) is a member of the epidermal growth factor (EGF) family and is expressed in a plethora of cancers. Tumour growth and metastasis were decreased by AREG silencing in an orthotopic model of pancreatic ca...
TMPK-00870	AREG Protein, Mouse, Recombinant (hFc)	Mouse	HEK293 Cells
	Amphiregulin (AREG) is a ligand of the epidermal growth factor receptor (EGFR), a widely expressed transmembrane tyrosine kinase. AREG is synthesized as a membrane-anchored precursor protein that can engage in juxtacrine...
TMPK-01019	EPHA5 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	The aim of the present study was to evaluate ephrin type-A receptor 5 (EphA5) expression and its clinicopathological significance in gastric cancer. Gastric cancer tissues were analyzed by immunohistochemistry. The assoc...
TMPK-00612	CSPG5 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	CALEB also known as chondroitin sulfate proteoglycan (CSPG)5 or neuroglycan C, is a neural chondroitin sulfate-containing and epidermal growth factor (EGF)-domain-containing transmembrane protein that is implicated in sy...
TMPJ-00517	WIF-1 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Wnt Inhibitory Factor 1 (WIF1) is a secreted protein, which binds WNT proteins and inhibits their activities. WNT proteins are extracellular signaling molecules involved in the control of embryonic development. WIF1 cont...
TMPY-03440	Sts1 Protein, Human, Recombinant (His)	Human	E. coli
	UBASH3B contains a ubiquitin associated domain at the N-terminus, an SH3 domain, and a C-terminal domain with similarities to the catalytic motif of phosphoglycerate mutase. UBASH3B was found to inhibit endocytosis of ep...
TMPY-00624	PEAR1 Protein, Rat, Recombinant (His)	Rat	Baculovirus Insect Cells
	Platelet endothelial aggregation receptor-1 (PEAR1), an epidermal growth factor repeat-containing transmembrane receptor, is known to participate in platelet contact-induced activation. Platelet endothelial aggregation r...
TMPK-00691	EGFRVIII Protein, Human, Recombinant (His & Avi)	Human	HEK293 Cells
	The epidermal growth factor receptor (EGFR) is overexpressed in a variety of human epithelial tumors, often as a consequence of gene amplification. Tumors with EGFR gene amplification frequently contain EGFR gene rearran...
TMPK-00690	EGFRVIII Protein, Human, Recombinant (His & Avi), FITC-Labeled	Human	HEK293 Cells
	The epidermal growth factor receptor (EGFR) is overexpressed in a variety of human epithelial tumors, often as a consequence of gene amplification. Tumors with EGFR gene amplification frequently contain EGFR gene rearran...
------------------------ More ------------------------

EGFR Protein, Cynomolgus, Recombinant (His)

TMPY-04818

Species: Cynomolgus

Expression System: HEK293 Cells

EGF Protein, Mouse, Recombinant (Yeast)

TMPY-06984

Species: Mouse

Expression System: P. pastoris (Yeast)

EGF Protein, Human, Recombinant

TMPY-01560

Species: Human

Expression System: E. coli

EGF Protein, Human, Recombinant (hFc)

TMPY-01062

Species: Human

Expression System: HEK293 Cells

EGFR Protein, Mouse, Recombinant (His)

TMPY-02676

Species: Mouse

Expression System: HEK293 Cells

EGFR Protein, Human, Recombinant (aa 668-1210, His & GST)

TMPY-04529

Species: Human

Expression System: Baculovirus Insect Cells

EGFR Protein, Human, Recombinant (His)

TMPY-00742

Species: Human

Expression System: HEK293 Cells

EGF Protein, Rat, Recombinant

TMPY-04220

Species: Rat

Expression System: E. coli

EGFR Protein, Rat, Recombinant (His)

TMPY-02958

Species: Rat

Expression System: HEK293 Cells

EGFR Protein, Canine, Recombinant (His)

TMPY-03724

Species: Canine

Expression System: Baculovirus Insect Cells

EGFR Protein, Feline, Recombinant (His)

TMPY-06524

Species: Feline

Expression System: Baculovirus Insect Cells

EGFR Protein, Rhesus, Recombinant (hFc)

TMPY-00128

Species: Rhesus

Expression System: HEK293 Cells

EGF Protein, Canine, Recombinant

TMPY-04884

Species: Canine

Expression System: P. pastoris (Yeast)

EGF Protein, Canine, Recombinant (His)

TMPY-02539

Species: Canine

Expression System: E. coli

EGF Protein, Feline, Recombinant (hFc)

TMPY-06493

Species: Feline

Expression System: HEK293 Cells

EGF Protein, Mouse, Recombinant (hFc)

TMPY-02267

Species: Mouse

Expression System: HEK293 Cells

EGF Protein, Mouse, Recombinant (His)

TMPY-00220

Species: Mouse

Expression System: HEK293 Cells

EGFR Protein, Mouse, Recombinant (hFc)

TMPY-02675

Species: Mouse

Expression System: HEK293 Cells

BTC Protein, Mouse, Recombinant (His)

TMPJ-00058

Species: Mouse

Expression System: E. coli

proHB-EGF Protein, Human, Recombinant (His)

TMPJ-01286

Species: Human

Expression System: HEK293 Cells

EGFR Protein, Human, Recombinant (Isoform vIII, aa 1-375, His)

TMPY-05211

Species: Human

Expression System: Baculovirus Insect Cells

EGFR Protein, Human, Recombinant (aa 1-645, His & Avi), Biotinylated

TMPY-05612

Species: Human

Expression System: HEK293 Cells

EGFR Protein, Human, Recombinant (aa 1-378, His & Avi), Biotinylated

TMPY-05637

Species: Human

Expression System: Baculovirus Insect Cells

EGFR Protein, Human, Recombinant (Isoform Viii, hFc)

TMPY-05258

Species: Human

Expression System: Baculovirus Insect Cells

EGFR Protein, Human, Recombinant (Isoform vIII, His & Avi), Biotinylated

TMPY-06593

Species: Human

Expression System: HEK293 Cells

EGFR Protein, Human, Recombinant (hFc)

TMPY-01043

Species: Human

Expression System: HEK293 Cells

EGFR Protein, Human, Recombinant (Isoform vIII, aa 1-378, His)

TMPY-06549

Species: Human

Expression System: HEK293 Cells

EGFR vIII Protein, Human, Recombinant (His & Avi), Biotinylated

TMPJ-00646

Species: Human

Expression System: HEK293 Cells

EGFR vIII Protein, Human, Recombinant (His)

TMPJ-00648

Species: Human

Expression System: HEK293 Cells

EGFR vIII Protein, Human, Recombinant (hFc)

TMPJ-00647

Species: Human

Expression System: HEK293 Cells

EGFL8 Protein, Mouse, Recombinant (His & Myc & SUMO)

TMPH-02645

Species: Mouse

Expression System: E. coli

CLEC14A Protein, Human, Recombinant (His)

TMPK-01073

Species: Human

Expression System: HEK293 Cells

HER2/ERBB2 Protein, Rat, Recombinant (E. coli, His)

TMPJ-00791

Species: Rat

Expression System: E. coli

PTP1B Protein, Human, Recombinant (His)

TMPY-04125

Species: Human

Expression System: E. coli

FGF-10 Protein, Human, Recombinant

TMPY-01061

Species: Human

Expression System: E. coli

VLDLR Protein, Human, Recombinant (His)

TMPY-01085

Species: Human

Expression System: HEK293 Cells

HER2/ErbB2 Protein, Human, Recombinant (His & Avi)

TMPK-00428

Species: Human

Expression System: HEK293 Cells

Tomoregulin-1 Protein, Mouse, Recombinant (hFc)

TMPY-04202

Species: Mouse

Expression System: HEK293 Cells

Tomoregulin-1 Protein, Human, Recombinant (hFc)

TMPY-00112

Species: Human

Expression System: HEK293 Cells

LRIG1 Protein, Mouse, Recombinant (His)

TMPY-02264

Species: Mouse

Expression System: HEK293 Cells

AREG Protein, Human, Recombinant

TMPJ-00859

Species: Human

Expression System: E. coli

AREG Protein, Human, Recombinant (hFc)

TMPK-00820

Species: Human

Expression System: HEK293 Cells

AREG Protein, Mouse, Recombinant (hFc)

TMPK-00870

Species: Mouse

Expression System: HEK293 Cells

EPHA5 Protein, Mouse, Recombinant (His)

TMPK-01019

Species: Mouse

Expression System: HEK293 Cells

CSPG5 Protein, Mouse, Recombinant (His)

TMPK-00612

Species: Mouse

Expression System: HEK293 Cells

WIF-1 Protein, Human, Recombinant (His)

TMPJ-00517

Species: Human

Expression System: HEK293 Cells

Sts1 Protein, Human, Recombinant (His)

TMPY-03440

Species: Human

Expression System: E. coli

PEAR1 Protein, Rat, Recombinant (His)

TMPY-00624

Species: Rat

Expression System: Baculovirus Insect Cells

EGFRVIII Protein, Human, Recombinant (His & Avi)

TMPK-00691

Species: Human

Expression System: HEK293 Cells

EGFRVIII Protein, Human, Recombinant (His & Avi), FITC-Labeled

TMPK-00690

Species: Human

Expression System: HEK293 Cells

--------- More ---------

Cat No.	Product Name
L2193	Anti-Liver Cancer Compound Library	1787 compounds
	1787 species of compounds related to liver cancer that can be used in anti-liver cancer drug development and pharmacological studies.
L2191	Anti-Breast Cancer Compound Library	1939 compounds
	A unique collection of 1939 compounds with anti-breast cancer therapeutic activity or targeting breast cancer’s major signaling pathways, can be used for anti-breast cancer drug discovery and mechanism study；

Libraries

Anti-Liver Cancer Compound Library

L2193

Compounds: 1787

Anti-Breast Cancer Compound Library

L2191

Compounds: 1939